About 20 passengers are in critical condition, while 26 other persons are injured and receiving treatment at the Winneba Trauma and Specialist Hospital in two separate accidents on the Kasoa-Cape Coast Highway.
Police say the three vehicles involved in the first accident were a Sprinter Benz bus, a KIA Rhino and a DAF Trailer.
In an interview with Adom News, Winneba Municipal Fire Service Commander, DOIII Kwesi Hughes revealed that the Kia Rhino tried to overtake the Sprinter bus but smashed into its side.
D0III Hughes said 8 of the passengers who had been trapped in the bus were taken to the hospital.
The impact of the crash left many in critical condition.
The Fire Service Commander, DOIII Kwesi Hughes explained that this was caused by overloading the vehicle with passengers.
He said the driver was having 36 passengers instead 23 passengers including foodstuff.
All 46 passengers are receiving treatment at Winneba Trauma and Specialist Hospital.